Controlled biosynthesis of odd-chain fuels and chemicals via engineered modular metabolic pathways

Controlled biosynthesis of odd-chain fuels and chemicals via engineered modular metabolic pathways.

Microbial systems are being increasingly developed as production hosts for a wide variety of chemical compounds. Broader adoption of microbial synthesis is hampered by a limited number of high-yielding natural pathways for molecules with the desired physical properties, as well as the difficulty in functionally assembling complex biosynthetic pathways in heterologous hosts. Here, we address bot...

Fuels and Chemicals from Biomass

Production of fuels and chemicals from xylose by engineered Saccharomyces cerevisiae: a review and perspective

Efficient xylose utilization is one of the most important pre-requisites for developing an economic microbial conversion process of terrestrial lignocellulosic biomass into biofuels and biochemicals. A robust ethanol producing yeast Saccharomyces cerevisiae has been engineered with heterologous xylose assimilation pathways. A two-step oxidoreductase pathway consisting of NAD(P)H-linked xylose r...

Clean Fuels & Chemicals

Fuel cells are receiving widespread attention as an alternate source for clean energy, and one of the most important developments are proton-exchange membrane fuel cells (PEMFC) which operate using hydrogen at low temperatures. In the U.S., there is a considerable effort underway to develop H2 as the preferred fuel due to the potential for decreasing our dependence on imported oil, and the envi...

Production of Bio-Derived Fuels and Chemicals

The great demand for, and impending depletion of petroleum reserves, the associated impact of fossil fuel consumption on the environment, and volatility in the energy market have elicited extensive research on alternative sources of traditional petroleum-derived products such as biofuels and bio-chemicals. Fossil oil is largely associated with gasoline, however, approximately 6000 petroleum-der...